High Glycemic Index Diets Increase the Risk of Chronic Degenerative Disease

Long-term consumption of high-glycemic foods may increase oxidative stress and the risk of chronic degenerative diseases.

Glycemic index (GI) is a measure of the rate that the carbohydrates in a food or meal are digested and appear in the blood as glucose (sugar). Glycemic load is a way of measuring the total carbohydrates in a meal or diet with a mathematical adjustment for GI. These measurements can be used to simultaneously describe the quality (glycemic index) and quantity of carbohydrate in a meal or diet.

Investigators from several leading U.S. institutions recently investigated whether a diet with a high GI or GL is associated with greater oxidative stress by taking specific measurements in nearly 300 healthy adults.

Researchers concluded that chronic consumption of high-GI foods may lead to chronically high oxidative stress, increasing the risk for several degenerative diseases. A low-GI diet, not a low carbohydrate diet, appears to be beneficial in reducing oxidative stress.